| Does It Matter Where We Measure Blood Pressure? | |
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MedLine Citation:
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PMID: 22300350 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Although blood pressure measured at the brachial artery plays a central role in our understanding and management of cardiovascular risk, in recent years great emphasis has been placed on the importance of central blood pressure. It seems straightforward that knowledge of the blood pressure directly affecting the major organs is important for understanding the pathophysiology and treatment of cardiovascular risk. However, the field has been troubled by controversies over measurement techniques and difficulty in designing therapies to modify central but not peripheral blood pressure. In this review we will consider the physiology underlying the change in blood pressure through the arterial tree and how central blood pressure can be measured. In addition, we will review the evidence regarding the relationship of central BP to cardiovascular disease and the effects of treatment. New measurement techniques and evidence regarding the specific benefits of therapies in modulating central haemodynamics mean that this is a rapidly developing area and understanding the concept of central blood pressure will be vital in the future © 2012 The Authors. British Journal of Clinical Pharmacology © 2012 The British Pharmacological Society. |
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Authors:
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LA Tomlinson; Ib Wilkinson |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-2-2 |
Journal Detail:
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Title: British journal of clinical pharmacology Volume: - ISSN: 1365-2125 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-3 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7503323 Medline TA: Br J Clin Pharmacol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 The Authors. British Journal of Clinical Pharmacology © 2012 The British Pharmacological Society. |
Affiliation:
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Clinical Pharmacology Unit, Addenbrooke's Hospital, Cambridge. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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