Document Detail


Does the E/e' index predict the maintenance of sinus rhythm after catheter ablation of atrial fibrillation?
MedLine Citation:
PMID:  20412266     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: The role of left ventricular (LV) diastolic dysfunction in recurrent atrial fibrillation (AF) after catheter ablation remains unknown. We investigated LV diastolic function using the ratio of early transmitral flow velocity (E) to early diastolic mitral annular velocity (e') and evaluated its predictive value for AF recurrence.
METHODS: One hundred three AF patients underwent transthoracic echocardiography before ablation and during 3 months of follow-up. Clinical and echocardiographic parameters of patients with maintained sinus rhythm were compared with those with recurrent AF.
RESULTS: Of 103 patients, 26 had recurrent AF during follow-up. The E/e' index was the best independent predictor of AF recurrence in a multivariate logistic regression model. A cutoff value of 11.2 for the E/e' measured before ablation was associated with a sensitivity of 80.8% and specificity of 81.8% (area under ROC curve, 0.840; 95% CI, 0.754-0.926) for AF recurrence. E/e' measured in sinus rhythm after ablation had an even better predictive power (area under ROC curve, 0.917; 95% CI, 0.850-0.983).
CONCLUSION: LV diastolic function was closely associated with AF recurrence after catheter ablation. The E/e' index can be used as an incremental predictor for AF recurrence after catheter ablation.
Authors:
Chen Li; Xunshi Ding; Juqian Zhang; Can Zhou; Yu Chen; Li Rao
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-04-16
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  27     ISSN:  1540-8175     ISO Abbreviation:  Echocardiography     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-26     Completed Date:  2010-12-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  630-6     Citation Subset:  IM    
Affiliation:
Department of Cardiology, West China Hospital of Sichuan University, Chengdu, China.
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MeSH Terms
Descriptor/Qualifier:
Aged
Atrial Fibrillation / complications*,  surgery*
Catheter Ablation*
Echocardiography / methods*
Female
Humans
Male
Middle Aged
Outcome Assessment (Health Care) / methods*
Prognosis
Reproducibility of Results
Sensitivity and Specificity
Treatment Outcome
Ventricular Dysfunction, Left / etiology*,  prevention & control*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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