Document Detail

Does Helicobacter pylori play a role in the development of chronic adenotonsillitis?
MedLine Citation:
PMID:  18691771     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Evaluation of the possible relationship between chronic adenotonsillitis and Helicobacter pylori (HP). PATIENTS AND METHODS: The study was performed prospectively on 91 pediatric patients who underwent tonsillectomy, adenoidectomy or adenotonsillectomy due to chronic tonsillitis and/or adenoiditis. The adenotonsillectomy specimens were examined for HP colonization by rapid urease test (RUT) and immunohistochemical evaluation. Before surgery, anti-HP IgG and IgA antibody titers were detected by enzyme linked immunosorbent assay (ELISA) test in venous blood samples of the patients. RESULTS: The RUT was positive in only two of the adenoidectomy specimens (2.2%) and in none of the tonsillectomy specimens. A positive result was not detected in any tonsillectomy specimens using immunohistochemical examination. Serum IgG antibody was positive in 21 (23%) patients, IgA antibody was detected in 7 (7.69%) patients and both tests were positive only in 3 (3.29%) patients. CONCLUSION: The results of this study suggested that HP would not colonize in tonsil tissue of patients with chronic tonsillitis.
Yusuf Vayisoglu; Cengiz Ozcan; Ayse Polat; Nuran Delialioglu; Kemal Gorur
Publication Detail:
Type:  Journal Article     Date:  2008-08-08
Journal Detail:
Title:  International journal of pediatric otorhinolaryngology     Volume:  72     ISSN:  0165-5876     ISO Abbreviation:  Int. J. Pediatr. Otorhinolaryngol.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-08     Completed Date:  2009-01-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003603     Medline TA:  Int J Pediatr Otorhinolaryngol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  1497-501     Citation Subset:  IM    
Mersin University, School of Medicine, Department of Otorhinolaryngology, Mersin, Turkey.
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MeSH Terms
Adenoids / microbiology*
Child, Preschool
Chronic Disease
Helicobacter Infections / diagnosis,  metabolism,  microbiology*
Helicobacter pylori / isolation & purification*
Immunoglobulin A / blood
Immunoglobulin G / blood
Prospective Studies
Tonsillitis / microbiology*
Urease / metabolism
Reg. No./Substance:
0/Immunoglobulin A; 0/Immunoglobulin G; EC

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