| Does the Bravo pH capsule affect esophageal motor function? | |
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MedLine Citation:
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PMID: 17760654 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to determine whether attachment of the Bravo pH monitoring capsule alters esophageal motility. Twenty normal subjects were studied with 36-channel high-resolution manometry before and after Bravo capsule placement. Subjects performed 10 5-mL water-swallows in both upright and supine positions and two 5-mL barium-swallows under fluoroscopy synchronized with manometry recordings. There was no significant change in basal esophagogastric junction (EGJ) pressure, EGJ relaxation pressure or peristaltic function before and after Bravo placement in either position. However, a 2-cm focus of augmented peristalsis was found corresponding to the position of the Bravo capsule. Ten subjects were aware of the capsule (7 had a mild foreign body sensation, 1 had mild discomfort, and 2 had chest pain altering daily activity or diet) while nine subjects were unaware of the capsule. Subjects who were aware of the capsule's presence exhibited a greater augmentation of peristalsis than those who were not (P < 0.05). Neither EGJ function nor peristaltic performance were significantly altered by the presence of a Bravo capsule. However, capsule presence was associated with a locus of augmented peristalsis and this phenomenon was most evident in subjects who perceived the presence of the Bravo capsule. |
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Authors:
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J E Pandolfino; Q Zhang; S K Ghosh; M P Roth; C Boniquit; P J Kahrilas |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E Volume: 20 ISSN: 1120-8694 ISO Abbreviation: Dis. Esophagus Publication Date: 2007 |
Date Detail:
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Created Date: 2007-08-31 Completed Date: 2008-01-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8809160 Medline TA: Dis Esophagus Country: Australia |
Other Details:
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Languages: eng Pagination: 406-10 Citation Subset: IM |
Affiliation:
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Department of Medicine, Northwestern University, The Feinberg School of Medicine, Chicago, Illinois 60611, USA. j-pandolfino@northwestern.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chest Pain / physiopathology Esophageal pH Monitoring / instrumentation* Esophagus / physiopathology* Female Fluoroscopy Humans Male Manometry Middle Aged Peristalsis / physiology* Supine Position / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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