| Does Blood Pressure Variability Modulate Cardiovascular Risk? | |
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MedLine Citation:
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PMID: 21465141 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Exactly how hypertension causes end organ damage and vascular events is poorly understood. Yet the concept that underlying "usual" blood pressure (BP) accounts for all BP-related risk of vascular events and for the benefits of BP-lowering drugs has come to underpin clinical guidelines on the diagnosis and treatment of hypertension. This article reviews evidence that variability in BP also predicts risk of stroke and other vascular events independently of mean BP and evidence that drug-class effects on variability in BP explain differences in the effectiveness of BP-lowering drugs in preventing stroke. |
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Authors:
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Peter M Rothwell |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-5 |
Journal Detail:
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Title: Current hypertension reports Volume: - ISSN: 1534-3111 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-5 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888982 Medline TA: Curr Hypertens Rep Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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University Department of Clinical Neurology, John Radcliffe Hospital, Level 6, West Wing, Headington, Oxford, OX3 9DU, UK, peter.rothwell@clneuro.ox.ac.uk. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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