Document Detail

Does Acute Physiology and Chronic Health Evaluation II Provide a Valid Metric to Directly Compare Disease Severity in Trauma versus Surgical Intensive Care Unit Patients?
MedLine Citation:
PMID:  23089446     Owner:  NLM     Status:  In-Data-Review    
The Acute Physiology and Chronic Health Evaluation II (APACHE II) score has never been validated to risk-adjust between critically ill trauma (TICU) and general surgical (SICU) intensive care unit patients, yet it is commonly used for such a purpose. To study this, we evaluated risk of death in TICU and SICU patients with pneumonia. We hypothesized that mortality for a given APACHE II would be significantly different and that using APACHE II to directly compare TICU and SICU patients would not be appropriate. We conducted a retrospective review of patients admitted to the TICU or SICU at a tertiary medical center over an 18-month period with pneumonia. Admission APACHE II scores, in-hospital mortality, demographics, and illness characteristics were recorded. One hundred eighty patients met inclusion criteria, 116 in the TICU and 64 in the SICU. Average APACHE II scores were not significantly different in the TICU versus SICU (25 vs 24; P = 0.4607), indicating similar disease severity; overall mortality rates, however, were significantly different (24 vs 50%; P = 0.0004). Components of APACHE II, which contributed to this mortality differential, were Glasgow Coma Score, age, presence of chronic health problems, and operative intervention. APACHE II fails to provide a valid metric to directly compare the severity of disease between TICU and SICU patients with pneumonia. These groups represent distinct populations and should be separated when benchmarking outcomes or creating performance metrics in ICU patients. Improved severity scoring systems are needed to conduct clinically relevant and methodologically valid comparisons between these unique groups.
Robert D Becher; Michael C Chang; J Jason Hoth; Jennifer L Kendall; H Randall Beard; Preston R Miller
Related Documents :
17164996 - One third of japanese patients with rheumatoid arthritis use complementary and alternat...
25312446 - Pharmaco-utilisation and related costs of drugs used to treat schizophrenia and bipolar...
11824966 - Tumor necrosis factor-alpha gene polymorphism in severe and mild-moderate rheumatoid ar...
12969986 - Clinical course of patients with wasp gene mutations.
6893526 - High prevalence of cervical dysplasia in std clinic patients warrants routine cytologic...
12787966 - Estrogen replacement therapy and frontotemporal dementia.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American surgeon     Volume:  78     ISSN:  1555-9823     ISO Abbreviation:  Am Surg     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370522     Medline TA:  Am Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1261-9     Citation Subset:  IM    
Acute Care Surgery Service, Department of General Surgery, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The use of bioabsorbable staple-line reinforcement performing stapled hemorrhoidopexy to decrease th...
Next Document:  Early Repair of Pelvic and Abdominal Nonurological Surgery-Induced Iatrogenic Ureteral Injuries in T...