Document Detail

Documented cases of post-transfusion malaria occurring in England: a review in relation to current and proposed donor-selection guidelines.
MedLine Citation:
PMID:  16101687     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND OBJECTIVES: Although uncommon, five cases of transfusion-transmitted malaria have been documented in England over the last 20 years. With the reappearance onto the market of high-quality malaria antibody assays, and by utilizing the results of analysis of these five cases, it has been possible to review the donor malaria-deferral guidelines. MATERIALS AND METHODS: Details of the five cases of post-transfusion malaria were reviewed against the proposed new donor-deferral guidelines for malaria. RESULTS: Three of the five cases of post-transfusion malaria were directly attributable to the deferral guidelines, allowing infectious donors to be bled. CONCLUSIONS: The proposed new guidelines will prevent further cases of transmission from semi-immune individuals.
A D Kitchen; J A J Barbara; P E Hewitt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Vox sanguinis     Volume:  89     ISSN:  0042-9007     ISO Abbreviation:  Vox Sang.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-08-16     Completed Date:  2005-10-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0413606     Medline TA:  Vox Sang     Country:  England    
Other Details:
Languages:  eng     Pagination:  77-80     Citation Subset:  IM    
National Transfusion Microbiology Laboratories, National Blood Service, London, UK.
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MeSH Terms
Antigens, Protozoan
Blood Banks
Blood Donors*
Blood Transfusion / adverse effects*
Blood-Borne Pathogens
Disease Transmission, Infectious
Donor Selection
Malaria / blood,  diagnosis,  etiology*
Middle Aged
Practice Guidelines as Topic
Tropical Medicine
Reg. No./Substance:
0/Antigens, Protozoan

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