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DOCOSAHEXAENOIC ACID AFFECTS MARKERS OF INFLAMMATION AND MUSCLE DAMAGE AFTER ECCENTRIC EXERCISE.
MedLine Citation:
PMID:  25029008     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The effect of docosahexaenoic acid (DHA) on inflammatory and muscle damage response to acute eccentric exercise and to the subsequent initiation of a resistance- training program was studied in 41 untrained men. Subjects consumed either 2 g/d of either DHA or placebo (PL) for 28 d prior to a 17 d exercise phase (d 1 to d 17) that began with an eccentric exercise bout of the elbow flexors (d 1). For analysis, the exercise period was further divided into an acute response phase (d 1-4). Isometric muscle strength (STR), range of motion (ROM), and soreness (DOMS) were measured on d 1 2, 3, 4, 7, 12, 17. Fasted blood was measured for interleukin-6 (IL-6), interleukin-1 receptor antagonist, C-reactive protein (CRP) and creatine kinase (CK) on d 1, 2, 4. Serum CK and CRP were also measured in blood collected on d 7, 12, 17. In the acute phase, DHA significantly reduced the serum CK (12.5%) and the IL-6 response (32%) but did not affect STR or DOMS. Over the entire 17 d resistance exercise period, DOMS area under the curve was 183.2 ± 96.2 for DHA and 203.2 ± 120.9 for PL (p=0.054) and the CK response was numerically lower for DHA (p = 0.093). DHA supplementation reduced some but not all indicators of muscle damage and inflammation in the four days after an acute eccentric exercise bout but did not significantly affect the response to initiation of resistance exercise.
Authors:
Frank M DiLorenzo; Christopher J Drager; Janet Walberg Rankin
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-7-15
Journal Detail:
Title:  Journal of strength and conditioning research / National Strength & Conditioning Association     Volume:  -     ISSN:  1533-4287     ISO Abbreviation:  J Strength Cond Res     Publication Date:  2014 Jul 
Date Detail:
Created Date:  2014-7-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9415084     Medline TA:  J Strength Cond Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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