Document Detail

Do temporal artery duplex ultrasound findings correlate with ophthalmic complications in giant cell arteritis?
MedLine Citation:
PMID:  19179409     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Ophthalmic complications are common in acute GCA. Do temporal artery ultrasound and clinical parameters correlate with the occurrence and severity of ophthalmic complications? METHODS: The results of temporal artery ultrasound examinations are compared with the occurrence of anterior ischaemic optic neuropathy (AION), central retinal artery occlusion (CRAO), branch retinal artery occlusion (BRAO), diplopia and amaurosis fugax in 222 consecutive patients with newly diagnosed, active GCA. RESULTS: Temporal artery ultrasound displayed vasculitic wall swelling (halo), stenoses and/or acute occlusions in 84% (58% in 67 large-vessel GCA patients and 95% in 155 patients without proximal arm vasculitis). Ophthalmic complications occurred in 64 (29%), AION in 30 (14%), CRAO in 7 (3%), BRAO in 2 (1%), amaurosis fugax in 16 (7%) and diplopia in 9 patients (4%). Ophthalmic complications were insignificantly more common if temporal artery ultrasound was positive (31 vs 17%; P = 0.11) as a greater number of patients without arm vasculitis showed eye involvement (34 vs 18%; P = 0.02). The number of pathological temporal artery segments, presence of stenoses or bilateral findings did not correlate with ophthalmic complications. Age >or= 72 yrs at diagnosis correlated with a higher incidence of ophthalmic complications. CONCLUSION: Ophthalmic complications occurred less frequently if proximal arm vasculitis was present. Findings of temporal artery ultrasound did not correlate with eye complications.
Wolfgang A Schmidt; Andreas Krause; Bernd Schicke; Jörn Kuchenbecker; Erika Gromnica-Ihle
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-01-29
Journal Detail:
Title:  Rheumatology (Oxford, England)     Volume:  48     ISSN:  1462-0332     ISO Abbreviation:  Rheumatology (Oxford)     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-03-18     Completed Date:  2009-05-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883501     Medline TA:  Rheumatology (Oxford)     Country:  England    
Other Details:
Languages:  eng     Pagination:  383-5     Citation Subset:  AIM; IM    
Medical Centre for Rheumatology Berlin-Buch, Berlin, Germany.
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MeSH Terms
Aged, 80 and over
Amaurosis Fugax / complications,  ultrasonography
Chi-Square Distribution
Diplopia / complications,  ultrasonography
Eye Diseases / complications*,  ultrasonography*
Giant Cell Arteritis / complications*,  ultrasonography*
Middle Aged
Optic Neuropathy, Ischemic / complications,  ultrasonography
Sensitivity and Specificity
Statistics, Nonparametric
Temporal Arteries / ultrasonography*
Ultrasonography, Doppler, Color*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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