Document Detail


Do repeatedly nondiagnostic fine needle aspirations of thyroid nodules predict malignancy risk?
MedLine Citation:
PMID:  25171877     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Fine needle aspiration biopsy (FNAB) is a common, minimally invasive, cost-effective, and rapid method to manage thyroid nodules, but nondiagnostic FNAB (ND-FNAB) is still a common problem due to high prevalence (2%-20%). Our purpose in this study is to investigate risk of malignancy of repeating ND-FNABs and correlation between clinical and ultrasound findings. Our cohort study included 75 patients who had 2 or more times ND-FNABs and, finally, undergone surgical resection. We evaluated demographic, clinical, ultasonographic, and pathologic features. Fifty-seven patients were female, and 22 patients were male. Seventy-five patients' histopathologic results were 76% (n = 57) benign and 24% (n = 18) malignant. Of malignant nodules, 94.4% (n = 17) were papillary carcinoma, whereas 5.6% (n = 1) were follicular carcinoma. We did not find any predictive factor for malignancy and any differences associated with clinical and ultrasonographic features between benign and malignant nodules. Reaspiration followed by surgery for appropriate patients is recommended.
Authors:
Dilek Arpaci; Didem Ozdemir; Neslihan Cuhaci; Gulten Kiyak; Abdussamet Yalcin; Soner Akbaba; Aylin Kilicyazgan; Reyhan Ersoy; Bekir Cakir
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-8-16
Journal Detail:
Title:  Annals of diagnostic pathology     Volume:  -     ISSN:  1532-8198     ISO Abbreviation:  Ann Diagn Pathol     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-8-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9800503     Medline TA:  Ann Diagn Pathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
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