| Do reduced multiples do better? | |
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MedLine Citation:
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PMID: 15279819 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Dramatic successes in infertility care have allowed millions of previously fertile women to have their own children. However, an epidemic of multiple pregnancies has resulted, with catastrophic increases in morbidity and mortality, and in the economic costs to society. Multifetal pregnancy reduction (MFPR) has been used to decrease fetal number in the late first trimester and has dramatically improved outcomes. Recent data suggest that pregnancies starting with three or four, and in some cases five fetuses, which are reduced to twins, do as well as starting with twins. Patients with triplets do better reduced to twins. Reduction to a singleton is becoming more common, particularly for women over 40. Combining MFPR with chorionic villus sampling in patients over 30 years of age has enabled couples to maximize the health of the resultant children. |
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Authors:
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Mark I Evans; Doina Ciorica; David W Britt |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Best practice & research. Clinical obstetrics & gynaecology Volume: 18 ISSN: 1521-6934 ISO Abbreviation: Best Pract Res Clin Obstet Gynaecol Publication Date: 2004 Aug |
Date Detail:
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Created Date: 2004-07-28 Completed Date: 2004-10-25 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 101121582 Medline TA: Best Pract Res Clin Obstet Gynaecol Country: England |
Other Details:
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Languages: eng Pagination: 601-12 Citation Subset: IM |
Affiliation:
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Columbia University, Institute for Genetics and Fetal Medicine, New York, NY, USA. mevans@chpnet.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Spontaneous
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etiology Age Factors Female Humans Infant, Newborn Infant, Premature Pregnancy Pregnancy Complications / etiology Pregnancy Outcome Pregnancy Reduction, Multifetal / ethics, methods* Pregnancy Trimester, First Pregnancy, Multiple / physiology* Reproductive Techniques, Assisted |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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