Document Detail

Do reduced multiples do better?
MedLine Citation:
PMID:  15279819     Owner:  NLM     Status:  MEDLINE    
Dramatic successes in infertility care have allowed millions of previously fertile women to have their own children. However, an epidemic of multiple pregnancies has resulted, with catastrophic increases in morbidity and mortality, and in the economic costs to society. Multifetal pregnancy reduction (MFPR) has been used to decrease fetal number in the late first trimester and has dramatically improved outcomes. Recent data suggest that pregnancies starting with three or four, and in some cases five fetuses, which are reduced to twins, do as well as starting with twins. Patients with triplets do better reduced to twins. Reduction to a singleton is becoming more common, particularly for women over 40. Combining MFPR with chorionic villus sampling in patients over 30 years of age has enabled couples to maximize the health of the resultant children.
Mark I Evans; Doina Ciorica; David W Britt
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Best practice & research. Clinical obstetrics & gynaecology     Volume:  18     ISSN:  1521-6934     ISO Abbreviation:  Best Pract Res Clin Obstet Gynaecol     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-07-28     Completed Date:  2004-10-25     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  101121582     Medline TA:  Best Pract Res Clin Obstet Gynaecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  601-12     Citation Subset:  IM    
Columbia University, Institute for Genetics and Fetal Medicine, New York, NY, USA.
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MeSH Terms
Abortion, Spontaneous / etiology
Age Factors
Infant, Newborn
Infant, Premature
Pregnancy Complications / etiology
Pregnancy Outcome
Pregnancy Reduction, Multifetal / ethics,  methods*
Pregnancy Trimester, First
Pregnancy, Multiple / physiology*
Reproductive Techniques, Assisted

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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