| Do prostate cancer patients suffer more from depressed mood or anhedonia? | |
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MedLine Citation:
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PMID: 23019092 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: This study aimed to compare the prevalence of depressed mood and anhedonia in a sample of men with prostate cancer (PCa) and to determine which of these key symptoms contributed most to the overall depressive status of that sample. METHOD: From Zung Self-rating Depression Scale (SDS) responses collected on 526 PCa patients, direct comparisons were made between the prevalence of the first two DSM-IV-TR symptoms of Major Depressive Episode. These symptoms were then tested for their predictive power on depression total score and Zung's criteria for 'clinically significant' depression. RESULTS: Mean scores for anhedonia were significantly higher than for depressed mood, and nearly 25 times as many patients had a high score for anhedonia as for depressed mood. The same pattern of results was apparent for those patients who had clinically significant levels of depression. Anhedonia was a more powerful predictor of total SDS depression score for the entire sample as well as for those patients with more severe depression. CONCLUSION: Because the biological basis for anhedonia is different to that for depressed mood, treatment options also differ for patients who show a preponderance of anhedonia in their depressive symptomatology. Suggestions are made for treatment choices for these PCa patients. Copyright © 2012 John Wiley & Sons, Ltd. |
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Authors:
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Christopher F Sharpley; Vicki Bitsika; David H R Christie |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-9-27 |
Journal Detail:
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Title: Psycho-oncology Volume: - ISSN: 1099-1611 ISO Abbreviation: Psychooncology Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-9-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9214524 Medline TA: Psychooncology Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 John Wiley & Sons, Ltd. |
Affiliation:
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Brain-Behaviour Research Group, University of New England, New South Wales, 4225, Australia. csharpley@onthenet.com.au. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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