Document Detail

Do horses suffer from irritable bowel syndrome?
MedLine Citation:
PMID:  20383978     Owner:  NLM     Status:  MEDLINE    
Irritable bowel syndrome (IBS) in man is not a single entity but has several causes. One of the most common forms has similarities with colic and laminitis in horses. Undigested food residues may pass from the small intestine into the colon where bacterial fermentation produces chemicals that lead to disease. In horses the consequences may be disastrous, but in healthy humans such malabsorption may not be harmful. After events such as bacterial gastroenteritis or antibiotic treatment, an imbalance of the colonic microflora with overgrowth of facultative anaerobes may arise, leading to malfermentation and IBS. It is not known whether such subtle changes may likewise be present in the microflora of horses who are susceptible to colic and laminitis. Metabolomic studies of urine and faeces may provide a suitable way forward to identify such changes in the horse's gut and thus help to identify more accurately those at risk and to provide opportunities for the development of improved treatment.
J O Hunter
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Equine veterinary journal     Volume:  41     ISSN:  0425-1644     ISO Abbreviation:  Equine Vet. J.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-04-13     Completed Date:  2010-05-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0173320     Medline TA:  Equine Vet J     Country:  England    
Other Details:
Languages:  eng     Pagination:  836-40     Citation Subset:  IM    
Gastroenterology Research Unit, Addenbrooke's Hospital, Cambridge, UK.
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MeSH Terms
Celiac Disease / complications,  veterinary
Colic / complications,  veterinary
Fermentation / physiology
Food Hypersensitivity / complications,  veterinary
Horse Diseases / etiology*,  therapy
Irritable Bowel Syndrome / complications,  veterinary*
Grant Support
//Wellcome Trust

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