Document Detail

Do fungi play a role in psoriatic nails?
MedLine Citation:
PMID:  17944702     Owner:  NLM     Status:  MEDLINE    
Onychomycosis is the most common disease of the nails and constitutes about a half of all nail abnormalities. Some factors like increasing age, male sex, repeated nail damage, genetic predispositions and underlying conditions, such as diabetes, immunodeficiency or peripheral arterial disease may predispose to develop onychomycosis. It is also suggested that abnormalities in nail morphology are the predisposing factors to onychomycosis. Psoriasis is one of the most common reasons of disturbed nail morphology and the spectrum of nail changes in psoriasis is very wide. Thus, there were suggestions that dystrophic nails in psoriatic patients lose their natural preventing barrier and therefore are more predisposed to fungal infection. This paper summarizes the knowledge about prevalence of onychomycosis among psoriatic patients and contains a literature review concerning this problem. Most authors report that the prevalence of onychomycosis in psoriatic patients is not higher than that in control population. However, especially yeasts and maybe moulds, probably as concomitant pathogens, are more often isolated from psoriatic patients than from non-psoriatic population. In reasonable cases, the mycological examination is required, especially when the clinical picture of the nails suggests the presence of fungal infection. In these cases, antifungal treatment may be beneficial for psoriatic patients.
Jacek C Szepietowski; Joanna Salomon
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Mycoses     Volume:  50     ISSN:  0933-7407     ISO Abbreviation:  Mycoses     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-10-19     Completed Date:  2007-12-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8805008     Medline TA:  Mycoses     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  437-42     Citation Subset:  IM    
Department of Dermatology, Venereology and Allergology, University of Medicine, Wroclaw, Poland.
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MeSH Terms
Foot Dermatoses / epidemiology*,  microbiology
Hand Dermatoses / epidemiology*,  microbiology
Onychomycosis / epidemiology*,  microbiology
Psoriasis / complications*,  epidemiology*,  microbiology

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