Document Detail

Do cytoprotective prostaglandins act as mild irritants?
MedLine Citation:
PMID:  7121138     Owner:  NLM     Status:  MEDLINE    
Of the various mechanisms proposed to explain the cytoprotective properties of prostaglandins, mucus discharge seems the most probable. Mild irritants capable of eliciting mucus release have also been shown to exert cytoprotection. It is suggested that prostaglandins act as mild irritants of the mucosa and that cytoprotection is a mucosal reaction to mild irritation, through stimulation of mucus discharge.
M Guslandi
Related Documents :
24967828 - Farmers' perceptions of local food procurement, mississippi, 2013.
15528928 - Allergenic potency of spices: hot, medium hot, or very hot.
17892258 - Fungal-stressed germination of black soybeans leads to generation of oxooctadecadienoic...
20448908 - Microwave-assisted maillard reactions for the preparation of advanced glycation end pro...
15545378 - Effects of cleaning duration and water temperature on oxytocin release and milk removal...
25304148 - Dietary advice for muscularity, leanness and weight control in men's health magazine: a...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods and findings in experimental and clinical pharmacology     Volume:  4     ISSN:  0379-0355     ISO Abbreviation:  Methods Find Exp Clin Pharmacol     Publication Date:  1982  
Date Detail:
Created Date:  1982-12-02     Completed Date:  1982-12-02     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7909595     Medline TA:  Methods Find Exp Clin Pharmacol     Country:  SPAIN    
Other Details:
Languages:  eng     Pagination:  317-20     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adenylate Cyclase / metabolism
Cell Survival / drug effects
Enzyme Activation / drug effects
Gastric Mucosa / blood supply,  secretion
Ions / metabolism
Mucus / secretion
Prostaglandins / pharmacology*
Regional Blood Flow / drug effects
Reg. No./Substance:
0/Ions; 0/Irritants; 0/Prostaglandins; EC Cyclase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effect of a concomitant treatment with ethynylestradiol and ascorbic acid on bile secretion in femal...
Next Document:  Effect of aminoglycoside antibiotics on the contractility of the uterus.