Document Detail

Do childhood diseases affect NHL and HL risk? A case-control study from northern and southern Italy.
MedLine Citation:
PMID:  16406019     Owner:  NLM     Status:  MEDLINE    
To investigate the association between non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL), and exposure to childhood diseases, we analyzed an Italian case-control study that included 225 histologically-confirmed incident cases of NHL, 62 HL cases, and 504 controls. After adjusting for confounding factors, all examined childhood diseases were negatively associated with HL. Measles was negatively associated with NHL, particularly follicular B-cell NHL. Our findings provide additional support to the hypothesis that infections by most common childhood pathogens may protect against HL or, at least, be correlated with some other early exposure, which may lower the risk of HL in adulthood. In addition, our study shows that measles may provide a protective effect against NHL.
Maurizio Montella; Luigino Dal Maso; Anna Crispo; Renato Talamini; Ettore Bidoli; Maria Grimaldi; Aldo Giudice; Antonio Pinto; Silvia Franceschi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-01-06
Journal Detail:
Title:  Leukemia research     Volume:  30     ISSN:  0145-2126     ISO Abbreviation:  Leuk. Res.     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-06-12     Completed Date:  2007-09-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7706787     Medline TA:  Leuk Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  917-22     Citation Subset:  IM    
Servizio di Epidemiologia, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy.
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MeSH Terms
Bacterial Infections / epidemiology*
Case-Control Studies
Chickenpox / epidemiology*
Hodgkin Disease / epidemiology*
Italy / epidemiology
Lymphoma, Non-Hodgkin / epidemiology*
Middle Aged
Paramyxoviridae Infections / epidemiology*
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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