Document Detail

Do catechol estrogens participate in the initiation of labor?
MedLine Citation:
PMID:  1659195     Owner:  NLM     Status:  MEDLINE    
To assess the role of catechol estrogens in the initiation of labor, we compared the levels in amniotic fluid during the second and third trimesters and from women undergoing cesarean section at term not in labor and those with spontaneous labor at term. Catechol estrogen concentrations in amniotic fluid increased significantly with the progress of pregnancy. Further, concentrations (mean +/- SE) were significantly higher in spontaneous labor at term (468.6 +/- 29.5 pg/ml) compared with those obtained during cesarean section (242.6 +/- 22.3 pg/ml) at term not in labor. We suggest that catechol estrogens, through their stimulating effects on prostaglandin synthesis, participate in the initiation of labor.
A Biswas; A Chaudhury; S C Chattoraj; S L Dale
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  165     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1991-12-03     Completed Date:  1991-12-03     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  984-7     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, Boston University School of Medicine, MA 02118.
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MeSH Terms
Amniotic Fluid / chemistry*
Cesarean Section
Estrogens, Catechol / analysis,  physiology*
Labor Onset / physiology*
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Grant Support
Reg. No./Substance:
0/Estrogens, Catechol

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