Document Detail

Do baseline atrial electrocardiographic and infarction patterns predict new-onset atrial fibrillation after ST-elevation myocardial infarction? Insights from the Assessment of Pexelizumab in Acute Myocardial Infarction Trial.
MedLine Citation:
PMID:  20444469     Owner:  NLM     Status:  In-Process    
BACKGROUND: Atrial infarction reportedly occurs in 0.7% to 52% of ST-elevation myocardial infarctions (STEMIs), up to two thirds of whom develop atrial fibrillation and flutter (AF). Prospective validation of electrocardiographic atrial infarction patterns is lacking. Hence, in STEMI patients treated with primary percutaneous coronary intervention, we examined whether baseline atrial electrocardiographic changes or atrial infarction patterns predicted new AF or mortality. METHODS: Within the Assessment of Pexelizumab in Acute Myocardial Infarction trial, a nested case-control study was conducted. Patients with new AF were matched 1:1 with controls, and baseline atrial electrocardiographic variables were examined. RESULTS: Abnormal P wave morphology (Liu minor criterion for atrial infarction) was significantly associated with new AF (adjusted odds ratio, 1.68; 1.03-2.73). This was also independently associated with 90-day mortality in the overall case-control cohort (adjusted hazard rate, 1.90; 1.04-3.46) and among patient with new-onset AF (adjusted hazard rate, 2.43; 1.22-4.84). CONCLUSIONS: Abnormal P wave morphology significantly predicted new AF and 90-day mortality in STEMI patients.
Sean van Diepen; Hany Siha; Yuling Fu; Cynthia M Westerhout; Renato D Lopes; Christopher B Granger; Paul W Armstrong;
Related Documents :
16174019 - Atrial fibrillation in patients with a dual defibrillator: characteristics of spontaneo...
17555929 - Does left atrial appendage peak emptying flow velocity predict the electrical energy re...
19563359 - Manifestation of left atrial events and interatrial frequency gradients in the surface ...
11685169 - Electromechanical dysfunction of the left atrium associated with interatrial block.
10688299 - Review of methods to predict and detect atrial fibrillation in post-cardiac surgery pat...
16310439 - Clinical determinants of sinus conversion by radiofrequency maze procedure for persiste...
11985919 - Time to onset of regional relaxation: feasibility, variability and utility of a novel i...
25428719 - Are all patients with psoriasis at increased risk for coronary artery disease?
7688199 - Late neovascularization of longstanding left ventricular mural thrombus--a case report.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-05-04
Journal Detail:
Title:  Journal of electrocardiology     Volume:  43     ISSN:  1532-8430     ISO Abbreviation:  J Electrocardiol     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-07-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  351-8     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Wolff-Parkinson-White alternans caused by adenosine stress test: supernormal conduction as an altern...
Next Document:  Nitric oxide and redox regulation in the liver: Part I. General considerations and redox biology in ...