Document Detail


Do anti-TNF-α drugs increase cancer risk in rheumatoid arthritis patients?
MedLine Citation:
PMID:  23138614     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Concern has been raised about an increased risk of lymphoma and skin cancers in patients with rheumatoid arthritis due to administration of anti-TNF-α drugs. Meta-analysis of observational data from registries as well as from randomized controlled trials has failed to show a significant increase in the risk of lymphoma when the sample size has been sufficiently large; skin cancer risk may represent a valid concern. Issues relating to interpretation of these data are discussed.
Authors:
David A Clark
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-9
Journal Detail:
Title:  Inflammopharmacology     Volume:  -     ISSN:  1568-5608     ISO Abbreviation:  Inflammopharmacology     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9112626     Medline TA:  Inflammopharmacology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Medicine, Health Sciences Center Rm. 3H1E, McMaster University, 1280 Main St. West, Hamilton, ON, L8S 4K1, Canada, clarkd@mcmcaster.ca.
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