Document Detail

Do the age of patients with tetralogy of fallot at the time of surgery and the applied surgical technique influence the reoperation rate? a single-center experience.
MedLine Citation:
PMID:  19370333     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: Primary repair of tetralogy of Fallot (TOF) has been favored in many centers for years now and results and advantages of this management seem to verify this procedure. The authors wanted to know, if the age at the time of surgery and the surgical techniques had an influence on the long-term results. PATIENTS AND METHODS: Between 1992 and 2003, 124 patients underwent complete repair of TOF at the University Hospital Münster, Germany. Patients were subdivided into two groups based on their age (< 1 year and > 1 year of age). Patients in whom a transannular patch (TAP) was used were compared with those without (NTAP), or in whom a conduit was used. RESULTS: Overall mortality was 8%, with an average age of death of 9.53 years (range 0.06-19.77 years). The patients' age at the time of surgery affected their survival as only two cases of death were reported among the group of children < 1 year of age (3.2%) whereas eight patients were older (12.9%; p = 0.0483). Six patients died within the first 30 days post surgery. Reoperation had to be performed in 21 cases, 13 (61.9%) of these patients were < 1 year of age at the time of surgery, eight were older (38.1%). A TAP, NTAP or conduit treatment did not show significant differences in long-term survival or freedom from reoperation. CONCLUSION: Early repair of TOF within the 1st year of life can be recommended, because mortality is lower than in patients treated at a higher age. There seems no significant difference in the reintervention rate between patients treated within the 1st year of life or later.
Christoph Gerling; Andreas Rukosujew; Hans-Gerd Kehl; Tonny D T Tjan; Andreas Hoffmeier; Johannes Vogt; Hans-Heinrich Scheld; Thomas Krasemann
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article     Date:  2009-04-16
Journal Detail:
Title:  Herz     Volume:  34     ISSN:  1615-6692     ISO Abbreviation:  Herz     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-04-16     Completed Date:  2009-07-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7801231     Medline TA:  Herz     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  155-60     Citation Subset:  IM    
Department of Pediatric Cardiology, University Children's Hospital Münster, Münster, Germany.
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MeSH Terms
Age Distribution
Cardiovascular Surgical Procedures / statistics & numerical data*
Child, Preschool
Germany / epidemiology
Infant, Newborn
Longitudinal Studies
Patient Selection
Reconstructive Surgical Procedures / statistics & numerical data*
Risk Assessment / methods
Risk Factors
Survival Analysis
Survival Rate
Tetralogy of Fallot / mortality*,  surgery*
Treatment Outcome
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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