Document Detail

Dizygotic triplet pregnancy following in-vitro fertilization.
MedLine Citation:
PMID:  8150931     Owner:  NLM     Status:  MEDLINE    
We present a case of dizygotic triplet pregnancy (mono-amniotic twins and a singleton) that, as far as we know, is the first reported one induced by artificial reproductive technology. It ended in the delivery of three healthy normal babies: two monozygotic twin boys and a girl. It appears that zygote splitting is significantly more common in patients treated with ovulation-inducing agents than in the general population. Also, in-vitro conditions of embryonic growth might influence the chances of multifetal gestation and the incidence of identical twinning. This may be due to changes in the physical properties of the zona pellucida and subsequent partial hatching of the pre-embryo. Evaluation of similar cases in the future may shed more light on the mechanism underlying their occurrence following in-vitro fertilization.
O Avrech; A Schoenfeld; S Amit; J Ovadia; B Fisch
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  8     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1993 Dec 
Date Detail:
Created Date:  1994-05-12     Completed Date:  1994-05-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  2240-2     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Beilinson Medical Centre, Petah-Tikva, Israel.
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MeSH Terms
Fertilization in Vitro*
Twins, Monozygotic*
Comment In:
Hum Reprod. 1994 Jul;9(7):1362-3   [PMID:  7962451 ]

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