Document Detail


Diverse molecular provocation of programmed cell death.
MedLine Citation:
PMID:  8918187     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The experimental study and manipulation of programmed cell death has been greatly assisted by the identification of genetic and pharmacological tools that can either induce or block cell lethality. This review discusses new insights into the molecular sensing of perturbations induced by such tools, as well as the possible consequences of this detection in determining cell survival.
Authors:
I E Wertz; M R Hanley
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Trends in biochemical sciences     Volume:  21     ISSN:  0968-0004     ISO Abbreviation:  Trends Biochem. Sci.     Publication Date:  1996 Oct 
Date Detail:
Created Date:  1996-12-18     Completed Date:  1996-12-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7610674     Medline TA:  Trends Biochem Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  359-64     Citation Subset:  IM    
Affiliation:
Department of Biological Chemistry, School of Medicine, University of California at Davis 95616, USA.
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MeSH Terms
Descriptor/Qualifier:
Amyloid / pharmacology
Apoptosis / drug effects,  genetics,  physiology*
Chelating Agents / pharmacology
Cytoskeleton / chemistry
DNA Damage / genetics
Ion Channels / metabolism
Oxidants / pharmacology
Receptors, Cell Surface / metabolism
Signal Transduction / genetics
Tumor Necrosis Factor-alpha / pharmacology
Chemical
Reg. No./Substance:
0/Amyloid; 0/Chelating Agents; 0/Ion Channels; 0/Oxidants; 0/Receptors, Cell Surface; 0/Tumor Necrosis Factor-alpha

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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