| Diverse biological activities of healthy foods. | |
| | |
MedLine Citation:
|
PMID: 11286123 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Diverse biological activities of 7 healthy foods [powdered pine needle, citrate-fermented sesame, powdered coffee, royal jelly, propolis, pollen and white sesame oil (extracted by super critical state (40 degrees C, 350 atmospheric pressure))] were investigated. The pine needle, sesame and powdered coffee was also extracted successively by ethanol and hot water, and lyophilized. The pine needle and coffee extracts, and propolis showed higher in vitro cytotoxic, bactericidal and oxidation activity, as compared with other 4 lipophilic healthy foods. However, propolis showed slightly lower, but significant cytotoxic and bactericidal activity with much reduced oxidation potential. ESR spectroscopy demonstrated that the cytotoxic activity of these extracts was closely related to their radical generation and O2- scavenging activities. Healthy food components may have both pro-oxidant and anti-oxidant properties. Pre-treatment of mice with pine needle, sesame or powdered coffee extract significantly reduced the lethality of bacterial infection, possibly due to their host-mediated action. These extracts failed to reduce the cytophatic effect of HIV-1 (human immunodeficiency virus) infection in MT-4 cells. No apparent acute toxicity was detected in mice by oral administration of 10 g/kg of these extracts. This data suggest the medicinal efficacy of healthy foods. |
| | |
Authors:
|
N Kobayashi; S Unten; H Kakuta; N Komatsu; M Fujimaki; K Satoh; C Aratsu; H Nakashima; H Kikuchi; K Ochiai; H Sakagami |
Related Documents
:
|
19444613 - Bioavailability of phenolic antioxidants associated with dietary fiber: plasma antioxid... 15563213 - Processing of rice husk autohydrolysis liquors for obtaining food ingredients. 20727933 - Risk assessment of thujone in foods and medicines containing sage and wormwood--evidenc... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: In vivo (Athens, Greece) Volume: 15 ISSN: 0258-851X ISO Abbreviation: In Vivo Publication Date: 2001 Jan-Feb |
Date Detail:
|
Created Date: 2001-04-04 Completed Date: 2001-08-02 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8806809 Medline TA: In Vivo Country: Greece |
Other Details:
|
Languages: eng Pagination: 17-23 Citation Subset: IM |
Affiliation:
|
Fujimi Bee House, Shiki, Saitama, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Anti-HIV Agents / toxicity Antioxidants / toxicity CD4-Positive T-Lymphocytes / cytology, virology Carcinoma, Squamous Cell Coffee Electron Spin Resonance Spectroscopy Fatty Acids / toxicity* Female HIV Infections / drug therapy Health Food* Humans Male Mice Mice, Inbred ICR Plant Extracts / toxicity Plant Leaves Pollen Propolis / toxicity* Sesame Oil / toxicity* Staphylococcal Infections / drug therapy Tumor Cells, Cultured |
| Chemical | |
Reg. No./Substance:
|
0/Anti-HIV Agents; 0/Antioxidants; 0/Coffee; 0/Fatty Acids; 0/Plant Extracts; 8008-74-0/Sesame Oil; 8031-67-2/royal jelly; 9009-62-5/Propolis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Changes in thymidine incorporation into tumor cells induced by supernatants of calcium-ionophore-tre...
Next Document: Preventive effects of a Chinese herbal medicine, hochu-ekki-to, on bone loss in ovariectomized rats.