| Divergent Route to Access Structurally Diverse 4-Quinolones via Mono or Sequential Cross-Couplings. | |
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MedLine Citation:
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PMID: 21082793 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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A divergent route was developed to access 3-iodo- and 6-chloro-3-iodo-4(1H)-quinolones for further elaboration via mono and/or sequential Suzuki-Miyaura cross-coupling to generate novel and medicinally important 4(1H)-quinolones. Copper- and palladium-catalyzed cyanations were used to functionalize the 4-quinolone core further. |
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Authors:
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R Matthew Cross; Roman Manetsch |
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Publication Detail:
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Type: Journal Article Date: 2010-11-17 |
Journal Detail:
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Title: The Journal of organic chemistry Volume: 75 ISSN: 1520-6904 ISO Abbreviation: J. Org. Chem. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985193R Medline TA: J Org Chem Country: United States |
Other Details:
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Languages: eng Pagination: 8654-7 Citation Subset: IM |
Affiliation:
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Department of Chemistry, University of South Florida, CHE205, 4202 East Fowler Avenue, Tampa, Florida 33620, United States. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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