| Diurnal variation is lost in preterm deliveries before 28 weeks of gestation. | |
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MedLine Citation:
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PMID: 20236106 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Preterm delivery is the primary cause of neonatal mortality and morbidity worldwide. Labour at term occurs as a culmination of maturational events in both the fetus and maternal uterus. This process exhibits diurnal variation, with the onset of labour being more common at night. We have confirmed that this diurnal variation is present in gestations between 28 and 36 weeks, but is absent below 28 weeks. We hypothesise that this is because before 28 weeks of gestation, the onset of labour may result from a pathological rather than a physiological process. This may have important implications regarding any pharmacological approach to the prevention and/or treatment of very early preterm labour. |
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Authors:
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M Vatish; P J Steer; A M Blanks; M Hon; S Thornton |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't Date: 2010-03-12 |
Journal Detail:
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Title: BJOG : an international journal of obstetrics and gynaecology Volume: 117 ISSN: 1471-0528 ISO Abbreviation: BJOG Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-04-08 Completed Date: 2010-06-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100935741 Medline TA: BJOG Country: England |
Other Details:
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Languages: eng Pagination: 765-7 Citation Subset: AIM; IM |
Affiliation:
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Warwick Medical School, Clinical Sciences Research Institute, Coventry, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Circadian Rhythm* Female Humans Labor Onset / physiology* Obstetric Labor, Premature / etiology*, physiopathology Pregnancy Pregnancy Trimester, Second / physiology Pregnancy Trimester, Third / physiology |
| Grant Support | |
ID/Acronym/Agency:
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//Medical Research Council |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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