Document Detail


Diurnal variation in angiotensin sensitivity in pregnancy.
MedLine Citation:
PMID:  8572017     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Our purpose was to study the diurnal variation in angiotensin II sensitivity. STUDY DESIGN: Angiotensin sensitivity tests were performed at 9 AM and at 2 PM in 12 normotensive pregnant women, with each woman serving as her own control. RESULTS: In all patients the effective pressor dose was higher in the afternoon. CONCLUSION: We suggest the greater sensitivity to angiotensin in the morning is related to an intrinsic circadian variation in vascular reactivity. When the result of an angiotensin sensitivity test is interpreted, the time of day it is performed should be taken into account.
Authors:
F M Delemarre; M A Didden; P A de Jong
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  174     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1996 Jan 
Date Detail:
Created Date:  1996-03-04     Completed Date:  1996-03-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  259-61     Citation Subset:  AIM; IM    
Affiliation:
Department of Obstetrics and Gynecology, Catharina Hospital Eindhoven, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Angiotensin II / administration & dosage,  pharmacology*
Blood Pressure / drug effects*
Circadian Rhythm*
Dose-Response Relationship, Drug
Female
Humans
Pregnancy / physiology*
Chemical
Reg. No./Substance:
11128-99-7/Angiotensin II

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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