Document Detail

Diurnal variation of arterial stiffness and subendocardial perfusion noninvasively assessed using applanation tonometry in healthy young men.
MedLine Citation:
PMID:  15989114     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Arterial stiffness is at least partially controlled by vascular tone. Vascular tone and underlying physiological processes, e.g. sympathetic activity, have been shown to follow diurnal variations. METHODS: This study investigated whether arterial stiffness and perfusion of subendocardial myocardium relative to cardiac workload show diurnal variations under physiological conditions. The aortic augmentation index (AIx) and subendocardial viability ratio (SEVR) were measured noninvasively in 26 healthy young men (27.6 +/- 3.4 years) using applanation tonometry at three different times (8:00, 12:00, 17:00) during one day. RESULTS: Mean AIx was significantly higher and mean SEVR significantly lower at 8:00 than at the later times. No significant differences were found between mean AIx and mean SEVR at 12:00 and at 17:00. CONCLUSIONS: The observed diurnal variations of AIx and SEVR will be of value when applanation tonometry is used in human research. In order to arrive at comparable data in longitudinal investigations, measurements should be made at similar times during the course of a day. In addition, our observation should assist in studies in which novel pharmacological compounds with activity on the vasculature are investigated.
Gerd Bodlaj; Jörg Berg; Georg Biesenbach
Related Documents :
8979644 - Effect of time of day on aerobic power in exhaustive high-intensity exercise.
17103374 - Trapping reactions of reactive carbonyl species with tea polyphenols in simulated physi...
8523494 - A comparative study of direct hemoperfusion and hemodialysis for the removal of glufosi...
18643254 - Spiral trajectory in the horizontal brazil nut effect.
19642904 - Antioxidant supplementation alters cytokine production from monocytes.
17575294 - Ionisation chamber containing boron as a neutron detector in medical accelerator fields.
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Wiener klinische Wochenschrift     Volume:  117     ISSN:  0043-5325     ISO Abbreviation:  Wien. Klin. Wochenschr.     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-07-01     Completed Date:  2005-08-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  21620870R     Medline TA:  Wien Klin Wochenschr     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  348-52     Citation Subset:  IM    
Second Department of Medicine, General Hospital Linz, Linz, Austria.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aorta / physiology*
Blood Flow Velocity / physiology
Blood Pressure / physiology*
Blood Pressure Determination / methods*
Circadian Rhythm / physiology*
Coronary Circulation / physiology*
Endocardium / physiology*
Manometry / methods*
Radial Artery / physiology*
Stress, Mechanical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Dynamics of inflammation parameters prior to tachyarrhythmias in critically ill patients.
Next Document:  Enhanced plasma catecholamine and cAMP response during the head-up tilt test in patients with vasova...