| Diurnal blood pressure variation in pheochromocytoma, primary aldosteronism and Cushing's syndrome. | |
| | |
MedLine Citation:
|
PMID: 14730325 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We examined circadian blood pressure (BP) variation (expressed as a relative night-time BP decline) in subjects with primary aldosteronism (78 patients), pheochromocytoma (n=45) and Cushing's syndrome (n=18). Subjects with aldosterone-producing adenoma (n=21) and pheochromocytoma (n=27) were also investigated after the tumour removal. In all, 65 patients with essential hypertension served as a control group. The night-time BP decline was significantly attenuated in all three forms of endocrine hypertension compared to the control group (primary aldosteronism P<0.0001, pheochromocytoma P<0.0001 for systolic and diastolic BP and Cushing's syndrome P<0.0001/<0.001 vs essential hypertension). In the case of pheochromocytoma, the absence of the night-time BP decrease was more prominent compared to the primary aldosteronism group (P=0.003/0.001) and for the diastolic BP also in comparison with the Cushing's syndrome group (P=0.03). Tumour removal led in both groups to the restoration of the previously altered circadian rhythm (aldosterone-producing adenoma: P=0.0005/0.0009; pheochromocytoma: P=0.001/0.0007). Our study demonstrates a blunted circadian BP variation in all forms of adrenal hypertension in comparison with essential hypertension. This reduction of the night-time BP decrease was more prominent in pheochromocytoma than in primary aldosteronism or Cushing's syndrome. |
| | |
Authors:
|
T Zelinka; B Strauch; L Pecen; J Widimský |
Related Documents
:
|
19812355 - The role of aldosterone in mediating the dependence of angiotensin hypertension on il-6. 15229305 - Serum aldosterone and the incidence of hypertension in nonhypertensive persons. 17884095 - A combined dexamethasone/corticotropin-releasing hormone test in patients with chronic ... 1560165 - Hypertension during reduction of long-term steroid therapy in young subjects with asthma. 3465915 - Role of vascular structure in blood pressure development of the spontaneously hypertens... 8820475 - Fish oil as an adjuvant in the treatment of hypertension. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of human hypertension Volume: 18 ISSN: 0950-9240 ISO Abbreviation: J Hum Hypertens Publication Date: 2004 Feb |
Date Detail:
|
Created Date: 2004-01-19 Completed Date: 2004-05-13 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8811625 Medline TA: J Hum Hypertens Country: England |
Other Details:
|
Languages: eng Pagination: 107-11 Citation Subset: IM |
Affiliation:
|
3rd Department of Medicine, First Faculty of Medicine, Charles University, General Faculty Hospital, Prague, Czech Republic. tzeli@lf1.cuni.cz |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adrenal Gland Neoplasms
/
physiopathology*,
surgery Adult Aged Aldosterone / biosynthesis Blood Pressure* Blood Pressure Determination Case-Control Studies Circadian Rhythm Cushing Syndrome / physiopathology* Female Humans Hyperaldosteronism / physiopathology*, surgery Hypertension / physiopathology* Male Middle Aged Pheochromocytoma / physiopathology*, surgery |
| Chemical | |
Reg. No./Substance:
|
52-39-1/Aldosterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Impact of the high-risk and mass strategies on hypertension control and stroke mortality in primary ...
Next Document: Secular decrease in blood pressure and reduction in mortality from cardiovascular disease in Israeli...