Document Detail


Diurnal and exercise-related variability of haemoglobin and reticulocytes in athletes.
MedLine Citation:
PMID:  20148373     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Haemoglobin (Hb) and Reticulocytes (Ret) are measured as indirect markers of doping in athletes. We studied the diurnal variation, the impact of exercise, fluid intake and ambient temperature in athletes on these parameters. Hourly venous blood samples were obtained from 36 male athletes of different disciplines (endurance (END) and non-endurance (NON-END)) over 12 h during a typical training day. Seven inactive subjects served as controls (CON). Hb and Ret were determined. A mixed model procedure was used to analyse the data. At baseline, Hb was similar for all groups, END showed lower Ret than NON-END and CON. Exercise showed a significant impact on Hb (+0.46 g/dl, p<0.001), the effect disappeared approximately 2 h after exercise. Hb decreased over the day by approximately 0.55 g/dl (p<0.01). There was no relevant effect on Ret. Fluid intake and ambient temperature had no significant effect. Hb shows significant diurnal- and exercise related variations. In an anti-doping context, most of these variations are in favour of the athlete. Blood samples taken after exercise might therefore provide reliable results and thus be used for the longitudinal monitoring of athletes if a timeframe for the re-equilibration of vascular volumes is respected.
Authors:
Y O Schumacher; M Wenning; N Robinson; P-E Sottas; G Ruecker; T Pottgiesser
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-02-10
Journal Detail:
Title:  International journal of sports medicine     Volume:  31     ISSN:  1439-3964     ISO Abbreviation:  Int J Sports Med     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-26     Completed Date:  2010-08-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  225-30     Citation Subset:  IM    
Copyright Information:
Copyright Georg Thieme Verlag KG Stuttgart . New York.
Affiliation:
Abteilung Sportmedizin, Medizinische Universitätsklinik Freiburg, Germany. olaf@msm1.ukl.uni-freiburg.de
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MeSH Terms
Descriptor/Qualifier:
Adult
Algorithms
Body Temperature Regulation
Case-Control Studies
Circadian Rhythm / physiology*
Doping in Sports
Drinking
Exercise / physiology*
Hemoglobins / analysis*
Humans
Male
Motor Activity / physiology
Physical Endurance / physiology
Reticulocyte Count
Reticulocytes* / cytology
Sports / physiology*
Temperature
Time Factors
Chemical
Reg. No./Substance:
0/Hemoglobins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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