| Diurnal and exercise-related variability of haemoglobin and reticulocytes in athletes. | |
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MedLine Citation:
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PMID: 20148373 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Haemoglobin (Hb) and Reticulocytes (Ret) are measured as indirect markers of doping in athletes. We studied the diurnal variation, the impact of exercise, fluid intake and ambient temperature in athletes on these parameters. Hourly venous blood samples were obtained from 36 male athletes of different disciplines (endurance (END) and non-endurance (NON-END)) over 12 h during a typical training day. Seven inactive subjects served as controls (CON). Hb and Ret were determined. A mixed model procedure was used to analyse the data. At baseline, Hb was similar for all groups, END showed lower Ret than NON-END and CON. Exercise showed a significant impact on Hb (+0.46 g/dl, p<0.001), the effect disappeared approximately 2 h after exercise. Hb decreased over the day by approximately 0.55 g/dl (p<0.01). There was no relevant effect on Ret. Fluid intake and ambient temperature had no significant effect. Hb shows significant diurnal- and exercise related variations. In an anti-doping context, most of these variations are in favour of the athlete. Blood samples taken after exercise might therefore provide reliable results and thus be used for the longitudinal monitoring of athletes if a timeframe for the re-equilibration of vascular volumes is respected. |
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Authors:
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Y O Schumacher; M Wenning; N Robinson; P-E Sottas; G Ruecker; T Pottgiesser |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-02-10 |
Journal Detail:
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Title: International journal of sports medicine Volume: 31 ISSN: 1439-3964 ISO Abbreviation: Int J Sports Med Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-26 Completed Date: 2010-08-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8008349 Medline TA: Int J Sports Med Country: Germany |
Other Details:
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Languages: eng Pagination: 225-30 Citation Subset: IM |
Copyright Information:
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Copyright Georg Thieme Verlag KG Stuttgart . New York. |
Affiliation:
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Abteilung Sportmedizin, Medizinische Universitätsklinik Freiburg, Germany. olaf@msm1.ukl.uni-freiburg.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Algorithms Body Temperature Regulation Case-Control Studies Circadian Rhythm / physiology* Doping in Sports Drinking Exercise / physiology* Hemoglobins / analysis* Humans Male Motor Activity / physiology Physical Endurance / physiology Reticulocyte Count Reticulocytes* / cytology Sports / physiology* Temperature Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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