| Disturbed solid-phase gastric emptying in functional dyspepsia: a meta-analysis. | |
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MedLine Citation:
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PMID: 9753269 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Functional dyspepsia is a common disorder with a diverse pathophysiological background, but the role of motility disorders in functional dyspepsia remains unclear. We aimed to quantify the relationship between disturbed gastric emptying and functional dyspepsia, using a meta-analytic approach. Through a structured literature search of Medline and Embase from 1983 to 1996, we selected all studies in which scintigraphic solid-phase gastric emptying was measured in both functional dyspeptic patients and controls. Seventeen studies involving 868 dyspeptic patients and 397 controls were pooled. Gastric emptying in patients with functional dyspepsia was 1.46 (1.23-1.69) times slower than controls; the proportion of patients with abnormally slow emptying was either 37% (34-40%, simple numeric pooling) or 39% (29-49%, weighted pooling). We conclude that gastric emptying of solids in patients with functional dyspepsia is 1.5 times slower than in healthy controls and that a significant delay of emptying is present in almost 40% of patients with functional dyspepsia. |
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Authors:
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A O Quartero; N J de Wit; A C Lodder; M E Numans; A J Smout; A W Hoes |
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Publication Detail:
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Type: Journal Article; Meta-Analysis |
Journal Detail:
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Title: Digestive diseases and sciences Volume: 43 ISSN: 0163-2116 ISO Abbreviation: Dig. Dis. Sci. Publication Date: 1998 Sep |
Date Detail:
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Created Date: 1998-10-09 Completed Date: 1998-10-09 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7902782 Medline TA: Dig Dis Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2028-33 Citation Subset: AIM; IM |
Affiliation:
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Department of General Practice, Universiteit Utrecht, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dyspepsia
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etiology*,
physiopathology* Gastric Emptying* Gastrointestinal Motility Humans |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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