Document Detail


Disturbances of rhythm in chronic lung disease.
MedLine Citation:
PMID:  584715     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Patients with chronic obstructive lung disease have a high incidence and wide variety of cardiac arrhythmias. These arrhythmias are often clinically significant and may be life threatening. Although they occur particularly in the context of acute respiratory failure, arrhythmias are not infrequent in clinically stable patients. The relatively high incidence of sudden arrhythmias seen in acute respiratory failure are associated with a very poor prognosis, in particular, ventricular premature beats and multifocal atrial tachycardia. Long-term electrocardiographic monitoring is valuable in increasing the detection of these arrhythmias and in assessing their clinical significance and response to therapy. The mechanisms producing these arrhythmias are poorly understood and probably multiple. However, disturbances of blood gases, blood pH, and electrolytes or the presence of cor pulmonale or associated coronary artery disease is probably important. The therapy of these arrhythmias must include efforts to improve the patient's ventilatory status as well as careful use of standard antiarrhythmic drugs. Further investigation is needed to define the mechanisms, determine the prognosis, and improve the therapy of the arrhythmias found in chronic obstructive lung disease.
Authors:
F D Biggs; S S Lefrak; R E Kleiger; R M Senior; G C Oliver
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Heart & lung : the journal of critical care     Volume:  6     ISSN:  0147-9563     ISO Abbreviation:  Heart Lung     Publication Date:    1977 Mar-Apr
Date Detail:
Created Date:  1977-05-20     Completed Date:  1977-05-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0330057     Medline TA:  Heart Lung     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  256-61     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Arrhythmias, Cardiac / etiology*,  physiopathology,  therapy
Death, Sudden / etiology
Digitalis Glycosides / therapeutic use
Electrocardiography
Humans
Lung Diseases, Obstructive / complications*,  mortality
Prognosis
Propranolol / therapeutic use
Respiratory Insufficiency / complications
Theophylline / therapeutic use
Chemical
Reg. No./Substance:
0/Digitalis Glycosides; 525-66-6/Propranolol; 58-55-9/Theophylline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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