| Disturbances of esophageal motility in eosinophilic esophagitis: a case series. | |
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MedLine Citation:
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PMID: 19707817 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Esophageal manometry (EM) findings were reviewed in 14 (13 male) adults diagnosed with eosinophilic esophagitis (EE). One had complete nonperistaltic contractions (amplitude range = 30-180 mmHg) and incomplete relaxation of the lower esophageal sphincter (LES), suggesting vigorous achalasia. After 6 months of steroid therapy the repeat EM showed near-normal findings. One had total aperistalsis with contraction amplitudes less than 10 mmHg and a weak LES pressure (8 mmHg), criteria suggesting scleroderma. Two had low-amplitude (<30 mmHg) nonperistaltic contractions limited to the mid-esophagus. Criteria for nutcracker esophagus were met in two patients. Isolated low LES pressure (<15 mmHg) was observed in four patients who were also receiving proton pump inhibitors, and the remainder had normal EM findings. Our results found that EE can mimic all the categories of EM disturbances, with approximately 50% of our patients having a major impairment of smooth muscle function. The EM abnormality can be reversed to normal in some cases with appropriate treatment for EE. |
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Authors:
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Reza A Hejazi; Savio C Reddymasu; Sandra Sostarich; Richard W McCallum |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-08-26 |
Journal Detail:
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Title: Dysphagia Volume: 25 ISSN: 1432-0460 ISO Abbreviation: Dysphagia Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8610856 Medline TA: Dysphagia Country: United States |
Other Details:
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Languages: eng Pagination: 231-7 Citation Subset: IM |
Affiliation:
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Division of Gastroenterology, Department of Medicine, Kansas University Medical Center, 3901 Rainbow Blvd., MS-1058, Kansas City, KS 66160-7350, USA. reza.abbaszdehhejazi@ttuhsc.edu |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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