| Distribution of wall shear stress in carotid plaques using. | |
| | |
MedLine Citation:
|
PMID: 21740799 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
BACKGROUND: Wall shear stress is an important factor in the destabilization of atherosclerotic plaques. The purpose of this study was to assess the distribution of wall shear stress in advanced carotid plaques using high resolution magnetic resonance imaging and computational fluid dynamics. METHODS: Eight diseased internal carotid arteries in seven patients were evaluated. High resolution magnetic resonance imaging was used to visualize the plaque structures, and the mechanic stress in the plaque was obtained by combining vascular imaging post-processing with computational fluid dynamics. RESULTS: Wall shear stresses in the plaques in all cases were higher than those in control group. Maximal shear stresses in the plaques were observed at the top of plaque hills, as well as the shoulders of the plaques. Among them, the maximal shear stress in the ruptured plaque was observed in the rupture location in three cases and at the shoulder of fibrous cap in two cases. The maximal shear stress was also seen at the region of calcification, in thrombus region and in the thickest region of plaque in the other three cases, respectively. CONCLUSION: Determination of maximal shear stress at the plaque may be useful for predicting the rupture location of the plaque and may play an important role in assessing plaque vulnerability. |
| | |
Authors:
|
Li-Na Jing; Pei-Yi Gao; Yan Lin; Bin-Bin Sui; Hai-Qiang Qin; Li Ma; Jing Xue |
Related Documents
:
|
16908559 - Global and region-specific analyses of apparent diffusion coefficient in dentatorubral-... 16087919 - Multiparametric mri and ultrasound findings in patients with internal carotid artery di... 14648559 - Amide proton transfer (apt) contrast for imaging of brain tumors. 21598899 - Incidence of false positive rotator cuff pathology in mris of patients with adhesive ca... 14970019 - Early diagnosis of central pontine myelinolysis with diffusion-weighted imaging. 15091129 - Inter- and intratumoral variability in magnetic resonance imaging of pleomorphic adenom... 3875249 - Surface-coil magnetic resonance imaging of the internal auditory canal. 21586929 - Effect of lapatinib on hepatic parenchymal enhancement on gadoxetate disodium (eob)-enh... 20625089 - Renal failure and posterior reversible encephalopathy syndrome in patients with thrombo... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Chinese medical journal Volume: 124 ISSN: 0366-6999 ISO Abbreviation: Chin. Med. J. Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-07-11 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7513795 Medline TA: Chin Med J (Engl) Country: China |
Other Details:
|
Languages: eng Pagination: 1465-9 Citation Subset: IM |
Affiliation:
|
Department of Radiology, Affiliated Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Alternatives to albumin administration in hepatocellular carcinoma patients undergoing hepatectomy: ...
Next Document: Clinicopathological and prognostic features of hepatoid adenocarcinoma of the stomach.