| Distribution of pressure-induced fast axonal transport abnormalities in primate optic nerve. An autoradiographic study. | |
| | |
MedLine Citation:
|
PMID: 6167249 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The distribution of transport abnormalities in primate optic nerve from eyes subjected to five hours of pressure elevation (perfusion pressure of 35 mm Hg) was studied. Tissue autoradiography and electron microscopy were used to localize regions of the lamina cribrosa with increased transport interruption. A preferential involvement by this transport abnormality involved the superior, temporal, and inferior portions, to the exclusion of the nasal portion, of the optic nerve head. This observation supports the hypothesis that transport interruption seen in this model may be pertinent to the study of clinical glaucomatous neuropathy. |
| | |
Authors:
|
R L Radius |
Related Documents
:
|
3492309 - Pesticide resistance mechanisms produced by field selection pressures on anopheles nige... 6126099 - Intraocular pressure reduction induced by hornet venom in the normal eye. 1781239 - Microfibril-microvessel connections in the uvea and optic nerve of the mammalian eye. 1264419 - The partial-punch: a new combined cataract-glaucoma operation. 22703929 - Cardiovascular and systemic microvascular effects of anti-vascular endothelial growth f... 655539 - Introduction of the ocusert ocular system to an ophthalmic practice. 14839 - The effect of guanethidine and hydrochlorothiazide on blood pressure and vascular tyros... 2815179 - Serum cholesterol and hemorrhagic stroke in the honolulu heart program. 15714439 - The vaginal pressure profile. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Archives of ophthalmology Volume: 99 ISSN: 0003-9950 ISO Abbreviation: Arch. Ophthalmol. Publication Date: 1981 Jul |
Date Detail:
|
Created Date: 1981-09-25 Completed Date: 1981-09-25 Revised Date: 2007-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 7706534 Medline TA: Arch Ophthalmol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1253-7 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Aotus trivirgatus Autoradiography Axonal Transport* Intraocular Pressure Optic Nerve / pathology, physiology* Perfusion / instrumentation, methods |
| Grant Support | |
ID/Acronym/Agency:
|
EY-01721/EY/NEI NIH HHS; EY-01931/EY/NEI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Peripapillary subretinal neovascularization in presumed sarcoidosis.
Next Document: Electron microscopy of the stria vascularis and its response to etacrynic acid. A study using electr...