Document Detail


Distribution of myocardial glycogen in turkey poults during development of furazolidone-induced cardiomyopathy.
MedLine Citation:
PMID:  7393859     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Furazolidone (FZ) at 700 ppm was added to feed mixtures fed turkey poults two weeks posthatching to induce experimental cardiomyopathy. Poults in the control pen received the same ration but without FZ. From ECG data obtained at weekly intervals, poults were selected for sacrifice at 3, 4, and 5 weeks of age. Myocardial samples from the right and left ventricular free walls were analyzed for glycogen by biochemical assay technics. Levels of glycogen were significantly (p less than .01) elevated in the FZ-treated poults at 3, 4, and 5 weeks of age. At all ages, the increase occurred in both the acid-soluble (TCA) and acid-insoluble (KOH) fractions with a proportionately greater increase in the TCA fraction. Results suggest that the effect of FZ on myocardial glycogen metabolism occurs very early and is more pronounced in the right ventricle than in the left ventricle even though both chambers may exhibit similar gross changes.
Authors:
C M Czarnecki; O A Evanson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Poultry science     Volume:  59     ISSN:  0032-5791     ISO Abbreviation:  Poult. Sci.     Publication Date:  1980 Jul 
Date Detail:
Created Date:  1980-09-28     Completed Date:  1980-09-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401150     Medline TA:  Poult Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1510-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cardiomyopathies / chemically induced,  metabolism,  veterinary*
Furazolidone
Glycogen / metabolism*
Myocardium / metabolism*
Poultry Diseases / chemically induced,  metabolism*
Turkeys*
Chemical
Reg. No./Substance:
67-45-8/Furazolidone; 9005-79-2/Glycogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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