Document Detail


Distribution of extractable mutagenic activity in steel foundry air particulates of different sizes.
MedLine Citation:
PMID:  6653507     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An Andersen 2000 sampler was used to collect different size classes of airborne particulate matter in a large steel foundry. When extracts of these particles were assayed for mutagenicity using the Ames Salmonella/S-9 assay, much of the mutagenic activity was found in particles of respirable size. Furthermore, mutagens requiring activation were distributed among the various size classes roughly in proportion to the total surface area of the particles with the smallest class (less than 1.1 micron) containing by far the largest amount of mutagenic activity. The distribution of direct-acting mutagenic activity was more variable and in some samples the bulk of this activity was in the largest size class (greater than 7.0 micron).
Authors:
D R McCalla; C Kaiser-Farrell; A Kerr; J N Lockington; E S Gibson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Environmental mutagenesis     Volume:  5     ISSN:  0192-2521     ISO Abbreviation:  Environ Mutagen     Publication Date:  1983  
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7909737     Medline TA:  Environ Mutagen     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  881-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Air Pollutants, Occupational / analysis*
Alloys*
Animals
Male
Mutagens / analysis*
Particle Size
Rats
Rats, Inbred Strains
Steel*
Time Factors
Chemical
Reg. No./Substance:
0/Air Pollutants, Occupational; 0/Alloys; 0/Mutagens; 12597-69-2/Steel

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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