| Distribution of echocardiographic parameters and their associations with cardiovascular risk factors in the Rotterdam Study. | |
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MedLine Citation:
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PMID: 20495954 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Insight into echocardiographic parameters in the general population may facilitate early recognition of ventricular dysfunction, reducing the population morbidity and mortality of heart failure. We examined the distribution of structural, systolic and diastolic echocardiographic parameters and their associations with cardiovascular risk factors in the Rotterdam Study, a population-based cohort study in men and women aged > or =55 years. Participants with prevalent heart failure, myocardial infarction and atrial fibrillation and flutter were excluded. Echocardiographic parameters were assessed using two-dimensional, M-mode and Doppler echocardiography. Echocardiograms were available in 4,425 participants. Structural parameters were generally larger in men, and most consistently associated with age, body mass index and blood pressure in both sexes. Prevalence of moderate or poor left ventricular systolic function was 3.9% in men and 2.1% in women. Age, body mass index and blood pressure were most consistently associated with systolic function. E/A ratio was lower in women than in men. Age and diastolic blood pressure were most consistently associated with E/A ratio in both sexes. In conclusion, ventricular systolic and diastolic dysfunction is present in asymptomatic individuals. Selected established cardiovascular risk factors are associated with structural, systolic and diastolic parameters. |
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Authors:
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Isabella Kardys; Jaap W Deckers; Bruno H Ch Stricker; Wim B Vletter; Albert Hofman; Jacqueline Witteman |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-05-22 |
Journal Detail:
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Title: European journal of epidemiology Volume: 25 ISSN: 1573-7284 ISO Abbreviation: Eur. J. Epidemiol. Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-14 Completed Date: 2010-10-20 Revised Date: 2013-05-29 |
Medline Journal Info:
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Nlm Unique ID: 8508062 Medline TA: Eur J Epidemiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 481-90 Citation Subset: IM |
Affiliation:
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Department of Epidemiology, Erasmus Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Distribution Body Mass Index Female Heart Failure, Diastolic / epidemiology*, ultrasonography* Heart Failure, Systolic / epidemiology*, ultrasonography* Humans Hypercholesterolemia / epidemiology Hypertension / epidemiology* Male Middle Aged Netherlands / epidemiology Prevalence Risk Factors Sex Distribution Ventricular Dysfunction, Left / epidemiology, ultrasonography* Ventricular Remodeling |
| Comments/Corrections | |
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