| Distribution and dynamics of transcription-associated proteins during parvovirus infection. | |
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MedLine Citation:
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PMID: 23035221 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Canine parvovirus (CPV) infection leads to reorganization of nuclear proteinaceous subcompartments. Our studies showed that virus infection causes a time-dependent increase in the amount of viral nonstructural protein NS1 mRNA. Fluorescence recovery after photobleaching showed that the recovery kinetics of nuclear transcription-associated proteins, TATA binding protein (TBP), transcription factor IIB (TFIIB), and poly(A) binding protein nuclear 1 (PABPN1) were different in infected and noninfected cells, pointing to virus-induced alterations in binding dynamics of these proteins. |
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Authors:
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Teemu O Ihalainen; Sami F Willman; Einari A Niskanen; Outi Paloheimo; Hanna Smolander; Juha P Laurila; Minna U Kaikkonen; Maija Vihinen-Ranta |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2012-10-03 |
Journal Detail:
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Title: Journal of virology Volume: 86 ISSN: 1098-5514 ISO Abbreviation: J. Virol. Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-11-20 Completed Date: 2013-01-28 Revised Date: 2013-04-16 |
Medline Journal Info:
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Nlm Unique ID: 0113724 Medline TA: J Virol Country: United States |
Other Details:
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Languages: eng Pagination: 13779-84 Citation Subset: IM |
Affiliation:
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Nanoscience Center, Department of Biological and Environmental Science, University of Jyväskylä, Finland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Compartmentation Parvoviridae Infections / metabolism* Parvovirus, Canine / isolation & purification Subcellular Fractions / metabolism* Transcription Factors / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Transcription Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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