Document Detail

Distribution of donor genome composition and its application in marker aided backcrossing.
MedLine Citation:
PMID:  11480178     Owner:  NLM     Status:  MEDLINE    
Conditional distribution was derived for the genome composition given the marker genotype of individuals from a backcross population. Genome size from donor was predicted by the mean. The precision of the prediction, indicated by the correlation with the unknown actual genome size from donor, was formulated by the variance and expressed as a function of the marker density. Results indicated that although high correlation can be obtained with a moderate marker density, say 40 cM per marker, the best individual in a large population has to be identified through a map of high density, say 10 to 20 cM per marker. For the best use of marker information in a marker aided backcrossing program for gene introgression, a stepwise marker genotyping and individual selection were suggested. That is, a preliminary selection can be made among all individuals but only on a few markers for each individual, and a fine selection would then be made among a few individuals but on more markers for each individual. This would be a very efficient method to increase the selection intensity in a large population but with a manageable number of marker genotyping for a gene introgression experiment.
C J Jinag; H D Mo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Yi chuan xue bao = Acta genetica Sinica     Volume:  28     ISSN:  0379-4172     ISO Abbreviation:  Yi Chuan Xue Bao     Publication Date:  2001  
Date Detail:
Created Date:  2001-08-01     Completed Date:  2001-08-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7900784     Medline TA:  Yi Chuan Xue Bao     Country:  China    
Other Details:
Languages:  eng     Pagination:  655-62     Citation Subset:  IM    
Laboratory of Quantitative Genetics, Yangzhou University, Yangzhou 225009, China.
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MeSH Terms
Crosses, Genetic*
Genetic Markers*
Reg. No./Substance:
0/Genetic Markers

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