Document Detail

Distribution of cardiac output during static exercise in the conscious cat.
MedLine Citation:
PMID:  7068479     Owner:  NLM     Status:  MEDLINE    
Blood flows to major organs were measured in conscious cats to study the changes in the distribution of cardiac output during voluntary static (isometric) exercise. Five animals were operantly conditioned to hold a bar against a fixed resistance for 30 s. Organ flows were measured during rest and exercise by injecting 25-micrometer radioactive microspheres into the left atrium or left ventricle. Increases were observed during exercise in heart rate (18%), mean arterial pressure (25%), left ventricular systolic pressure (17%), and rate of left ventricular development (26%). Static exercise produced significant changes in flow (ml . min-1 .g-1) to the kidneys (-1.09 +/- 0.24), spleen (-0.85 +/- 0.21), and exercising muscles (+0.13 +/- 0.08), while flows to liver, heart, brain, and nonexercising muscle were not significantly changed from control levels. Denervation of the left kidney abolished the decrease in flow to that kidney during exercise. Thus, static exercise appears to produce a significant increase in blood flow to exercising muscles and significant reductions in blood flow to spleen and kidneys. The reduction in renal blood flow is mediated by a neural mechanism.
G Diepstra; W Gonyea; J H Mitchell
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of applied physiology: respiratory, environmental and exercise physiology     Volume:  52     ISSN:  0161-7567     ISO Abbreviation:  J Appl Physiol Respir Environ Exerc Physiol     Publication Date:  1982 Mar 
Date Detail:
Created Date:  1982-06-14     Completed Date:  1982-06-14     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  7801242     Medline TA:  J Appl Physiol Respir Environ Exerc Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  642-6     Citation Subset:  IM; S    
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MeSH Terms
Blood Pressure
Cardiac Output*
Conditioning, Operant
Isometric Contraction*
Kidney / innervation
Muscles / blood supply
Physical Exertion*
Renal Circulation
Spleen / blood supply
Sympathetic Nervous System / physiology
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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