Document Detail


Distribution of Paenibacillus larvae spores among adult honey bees (Apis mellifera) and the relationship with clinical symptoms of American foulbrood.
MedLine Citation:
PMID:  18046600     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Knowledge of the distribution of Paenibacillus larvae spores, the causative agent of American foulbrood (AFB), among individual adult honey bees is crucial for determining the appropriate number of adult bees to include in apiary composite samples when screening for diseased colonies. To study spore distribution at the individual bee level, 500 honey bees were collected from different parts of eight clinically diseased colonies and individually analyzed for P. larvae. From the brood chamber and from the super, bees were randomly collected and individually put in Eppendorf vials. The samples were frozen as soon as possible after collection. Concurrently with sampling, each colony was visually inspected for clinical symptoms of AFB. The number of clinically diseased cells in the colony was visually estimated. All samples were cultured in the laboratory for P. larvae. The results demonstrate that the spores are not randomly distributed among the bees; some bees have much higher spore loads than others. It is also clear that as the proportion of contaminated bees increase, the number of spores from each positive bee also increases. The data also demonstrated a relationship between the number of clinically diseased cells and the proportion of positive bees in individual colonies. This relationship was used to develop a mathematical formula for estimating the minimum number of bees in a sample to detect clinical disease. The formula takes into account the size of the apiary and the degree of certainty with which one aims to discover clinical symptoms. Calculations using the formula suggest that adult bee samples at the colony level will detect light AFB infections with a high probability. However, the skewed spore distribution of the adult bees makes composite sampling at the apiary level more problematic, if the aim of the sampling is to locate lightly infected individual colonies within apiaries. The results suggest that false-negative culturing results from composite samples of adult bees from individual colonies with clinical symptoms of AFB are highly improbable. However, if single colonies have light infections in large apiaries, the dilution effect from uncontaminated bees from healthy colonies on the positive bees from diseased colonies may yield false-negative results at the apiary level.
Authors:
Anders Lindström
Publication Detail:
Type:  Journal Article     Date:  2007-11-29
Journal Detail:
Title:  Microbial ecology     Volume:  56     ISSN:  0095-3628     ISO Abbreviation:  Microb. Ecol.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-06-30     Completed Date:  2008-09-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7500663     Medline TA:  Microb Ecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  253-9     Citation Subset:  IM    
Affiliation:
Department of Ecology, Swedish University of Agricultural Sciences, Box 7044, 750 07, Uppsala, Sweden. anders.lindstrom@ekol.slu.se
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MeSH Terms
Descriptor/Qualifier:
Animals
Bees / growth & development,  microbiology*
Colony Count, Microbial
Gram-Positive Endospore-Forming Rods / isolation & purification*,  pathogenicity*,  physiology
Larva / microbiology*
Spores, Bacterial / isolation & purification*
United States

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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