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Distribution of Normal Nuchal Translucency Thickness: A Multicenter Study in Thailand.
MedLine Citation:
PMID:  21150163     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Aims: To establish the normative data distribution of nuchal translucency (NT) thickness in Thai fetuses. Methods: A cross-sectional multicenter study was conducted among 6,455 women with singleton pregnancies and gestational age between 10 and 14 weeks. For each case, the fetal crown-rump length (CRL) and NT were measured by transabdominal ultrasound. Transvaginal ultrasounds were used in poorly visualized cases. The distribution values of the NT thicknesses and their corresponding 10-mm CRL intervals between 45 and 84 mm were examined to obtain the median and 95th percentiles. Quantile regression modeling across the CRLs was performed to obtain the reference values. Results: Transabdominal ultrasound measurements were successfully done on 6,347 fetuses with 39 cases by the transvaginal route. Fetuses with CRL between 45 and 84 mm and normal outcomes made up a total of 4,352 cases. The mean (SD) gestational age, CRL and NT thickness were 12.5 (0.7) weeks, 60.2 (9.7) mm, and 1.15 (0.38) mm, respectively. The mean normal NT increased linearly with CRL. The quantile regression equation to predict the 95th percentile of the NT thickness (mm) was 0.727 + [0.017 × CRL (mm)]. Conclusions: The NT thickness in normal Thai fetuses was found to be thinner than in both Caucasian and other Asian populations.
Authors:
Ounjai Kor-Anantakul; Thitima Suntharasaj; Chitkasaem Suwanrath; Pharuhas Chanprapaph; Supatra Sirichotiyakul; Thawalwong Ratanasiri; Chutawadi Vuthiwong; Alan Geater
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-12-09
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  -     ISSN:  1423-002X     ISO Abbreviation:  -     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 S. Karger AG, Basel.
Affiliation:
Department of Obstetrics and Gynecology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
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