| Distribution of cerebral blood flow in the nucleus caudatus, nucleus lentiformis, and thalamus: a study of territorial arterial spin-labeling MR imaging. | |
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MedLine Citation:
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PMID: 20089720 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Purpose: To investigate the effect of variations in anatomic features of the circle of Willis on the perfusion territory to deep structures, including the nucleus caudatus, the nucleus lentiformis, and the thalamus. Materials and Methods: The ethics committee of the study institution approved the study protocol. A total of 159 patients with first-time clinical symptoms of cerebral ischemia were recruited. Contributions to the perfusion territory were visualized with territorial arterial spin-labeling magnetic resonance (MR) imaging. The anatomic features of the circle of Willis were evaluated with time-of-flight MR angiography. Perfusion territory contributions were compared among circle of Willis variants by using the Cochran-Mantel-Haenszel test. Results: The perfusion territory contributions to the deep-brain structures could be evaluated in 119 of 159 patients (75%). With a fetal-type circle of Willis (41 of 238 hemispheres; 17%), there was a contribution from the ipsilateral internal carotid artery to the thalamus in all 41 hemispheres (100%), compared with 96 of the 197 hemispheres (49%) without a fetal-type circle of Willis. In the 19 patients with a hypoplastic A1 segment, there was more often a contribution of the contralateral internal carotid artery to the perfusion of the nucleus caudatus (10 of 19; 53%) and the nucleus lentiformis (5 of 19; 26%). Conclusion: The perfusion territory contributions to deep-brain structures vary widely. These differences can be partly explained by variations in the anatomic features of the circle of Willis. (c) RSNA, 2010. |
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Authors:
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Jeroen Hendrikse; Esben Thade Petersen; Soke Miang Chng; Narayanaswamy Venketasubramanian; Xavier Golay |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-01-20 |
Journal Detail:
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Title: Radiology Volume: 254 ISSN: 1527-1315 ISO Abbreviation: Radiology Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-23 Completed Date: 2010-04-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 867-75 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, University Medical Center Utrecht, Utrecht, the Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Caudate Nucleus / blood supply* Cerebrovascular Circulation* Corpus Striatum / blood supply* Female Humans Image Processing, Computer-Assisted Linear Models Logistic Models Magnetic Resonance Angiography / methods* Male Middle Aged Spin Labels Thalamus / blood supply* |
| Chemical | |
Reg. No./Substance:
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0/Spin Labels |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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