Document Detail


Distortion product otoacoustic emissions and sensorineural hearing loss.
MedLine Citation:
PMID:  7741665     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
As other types of otoacoustic emissions, distortion product otoacoustic emissions (DPOAEs) allow the exploration of the active cochlear mechanisms known to take place in the outer hair cell system. Most authors consider that 2f1-f2 DPOAEs are generated in a cochlear region corresponding to the geometric mean (GM) of the primary frequencies. To verify the relevance of this hypothesis in clinical practice, DPOAEs were recorded at seven different frequencies, ranging from 0.5 to 4 kHz, in 81 hearing-impaired patients and in 24 normally hearing subjects. To test the hypothesis that DPOAEs reflect the hearing threshold at the frequency of the GM rather than at the 2f1-f2 frequency, this study compares the 2f1-f2 frequency and the GM of the primaries to the frequency of hearing loss. DPOAEs can be used to explore a large range of frequencies, especially at high frequencies, but responses at low frequencies are less reliable due to noise contamination. Secondly, DPOAEs can be recorded in ears that have a hearing threshold as high as 65 dB HL at the frequency corresponding to the GM of the primaries. Finally, DPOAE recordings show frequency specificity: i.e., hearing loss at a specific frequency correlates best with DPOAEs whose GM of primary frequencies corresponds to the frequency of the hearing loss. However, this frequency specificity is still unsatisfactory and decreases as the levels of primaries increase above 60 dB SPL. Moreover, DPOAE amplitude is too variable to predict hearing loss at a particular frequency, whereas DPOAE threshold allows a correct prediction of abnormal auditory threshold in more than 80% of the cases at frequencies above 1 kHz.
Authors:
A Moulin; J C Bera; L Collet
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Audiology : official organ of the International Society of Audiology     Volume:  33     ISSN:  0020-6091     ISO Abbreviation:  Audiology     Publication Date:    1994 Nov-Dec
Date Detail:
Created Date:  1995-06-02     Completed Date:  1995-06-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1273752     Medline TA:  Audiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  305-26     Citation Subset:  IM    
Affiliation:
Physiologie Sensorielle Audition et Voix, Unité associée au CNRS 1447, Hôpital Edouard-Herriot, Lyon, France.
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MeSH Terms
Descriptor/Qualifier:
Acoustic Impedance Tests
Adult
Audiometry, Pure-Tone
Auditory Threshold
Cochlea / physiopathology
Evoked Potentials, Auditory, Brain Stem
Female
Hearing / physiology
Hearing Loss, Sensorineural / diagnosis*,  physiopathology
Humans
Male
Middle Aged
Otoacoustic Emissions, Spontaneous*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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