| Distinguishing true coagulase-negative Staphylococcus infections from contaminants in the neonatal intensive care unit. | |
MedLine Citation:
|
PMID: 22499081 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Objective:To characterize true coagulase-negative Staphylococcus (CoNS) infections in infants receiving neonatal intensive care.Study Design:Retrospective cohort study of neonatal intensive care unit (NICU) infants with clinical sepsis and CoNS isolated from 2 blood cultures (BCs) or one BC and a sterile site (proved infection) or CoNS isolated from one BC and deemed significant after blinded data review (probable infection).Result:In all, 98% of 40 proved and 96% of 55 probable infections occurred in infants with birth weight (BW) <2000 g and gestation <34 weeks. Total central lines (CLs) placed, but not CL duration or presence in situ, predicted proved (odds ratio (OR) 3.5, 95% confidence interval (CI) 1.4 to 8.3; P=0.005) and probable infection (OR 2.7, 95% CI 1.3 to 5.6; P=0.007) by multivariate analysis as did lethargy and gastric residuals.Conclusion:True CoNS infection is unlikely in infants with BW >2000 g and gestation >34 weeks. Total CL required for care, lethargy and gastric residuals predicted true CoNS infection.Journal of Perinatology advance online publication, 12 April 2012; doi:10.1038/jp.2012.36. |
Authors:
|
C M Healy; C J Baker; D L Palazzi; J R Campbell; M S Edwards |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-4-12 |
Journal Detail:
|
Title: Journal of perinatology : official journal of the California Perinatal Association Volume: - ISSN: 1476-5543 ISO Abbreviation: - Publication Date: 2012 Apr |
Date Detail:
|
Created Date: 2012-4-13 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
1] Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA [2] Woman's Hospital of Texas, Houston, TX, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Novel D-?-A structured Zn(ii)-porphyrin dyes containing a bis(3,3-dimethylfluorenyl)amine moiety for...
Next Document: Efficacy of phototherapy devices and outcomes among extremely low birth weight infants: multi-center...