| Distinguishing between polymorphic forms of linezolid by solid-phase electronic and vibrational circular dichroism. | |
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MedLine Citation:
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PMID: 22434149 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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For the first time two crystalline forms of the same compound (linezolid polymorphs) were investigated by means of the solid-phase ECD and VCD spectra. The ECD spectra show distinct differences and the band at 221 nm serves as a diagnostic one because it is present in form II but absent in form III. The VCD spectra strongly differ in the diagnostic carbonyl absorption range exhibiting two relatively strong bands of opposite signs. |
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Authors:
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Jadwiga Frelek; Marcin Górecki; Marta Laszcz; Agata Suszczyńska; Elemér Vass; Wojciech J Szczepek |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-3-20 |
Journal Detail:
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Title: Chemical communications (Cambridge, England) Volume: - ISSN: 1364-548X ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-3-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610838 Medline TA: Chem Commun (Camb) Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Institute of Organic Chemistry of the Polish Academy of Sciences, ul. Kasprzaka 44/52, 01-224 Warsaw, Poland. jadwiga.frelek@icho.edu.pl. |
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