| Distinctive clinical features of bilateral Duane retraction syndrome. | |
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MedLine Citation:
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PMID: 20736120 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To compare the clinical characteristics of unilateral and bilateral forms of Duane retraction syndrome. METHODS: A retrospective chart review of patients with Duane syndrome over a 10-year span was performed. All participants underwent a complete medical and ophthalmologic examination at the time of diagnosis. Data collected included the following: sex, age at first visit, form (unilateral/bilateral), side, type, ocular duction and version, abnormal head position, best-corrected visual acuity, refractive errors, presence of strabismus, binocular function, and associated congenital anomalies. RESULTS: Of 94 patients identified, 17% were bilaterally affected. Of the bilateral patients, 12% had familial antecedents; 87.5% had the same type in both eyes with 75% bilateral type 1. Patients with bilateral Duane syndrome had significantly different visual acuity (mean, 0.1214 logMar vs 0.0035; p = 0.045), abnormal head position (56.25% vs 89%; p = 0.04), A or V patterns (69% vs 27.6%; p = 0.003), and associated congenital anomalies (50% vs 14%; p = 0.003) than patients with unilateral disease. There was also a suggestion of higher rates of ametropia, global vertical dysfunction, and abnormal stereoacuity in bilateral Duane syndrome that were not statistically significant. CONCLUSIONS: Patients with bilateral Duane syndrome had lower visual acuity, a lower incidence of abnormal head posture, and a higher incidence of A or V patterns and associated congenital anomalies. Bilateral Duane retraction syndrome seems to involve multiple instances of deinnervation and fibrosis, resulting in horizontal and vertical oculomotor deficits and functional impairments. |
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Authors:
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Emilie Zanin; Nicole Gambarelli; Danièle Denis |
Publication Detail:
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Type: Comparative Study; Journal Article; Multicenter Study |
Journal Detail:
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Title: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus Volume: 14 ISSN: 1528-3933 ISO Abbreviation: J AAPOS Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-25 Completed Date: 2011-01-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9710011 Medline TA: J AAPOS Country: United States |
Other Details:
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Languages: eng Pagination: 293-7 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2010 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved. |
Affiliation:
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Ophthalmology Department, North University Hospital, Chemin des Bourrelly, Marseille, France. emilie.zanin@etumel.univmed.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Child Child, Preschool Duane Retraction Syndrome / physiopathology* Eye Movements / physiology* Female Head Movements Humans Infant Male Middle Aged Oculomotor Muscles / physiopathology* Retrospective Studies Severity of Illness Index Vision, Binocular Visual Acuity / physiology* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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