| Distinction between postoperative recurrent glioma and delayed radiation injury using MR perfusion weighted imaging. | |
| | |
MedLine Citation:
|
PMID: 22141606 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Introduction: Distinction between postoperative recurrent glioma and radiation injury remains a tough diagnostic problem for routine imaging methods. The purpose of this study is to evaluate the differentiated effectiveness of perfusion weighted imaging (PWI) for the two entities. Methods: PWI was performed using Siemens 3.0-T MR system for 35 patients with new contrast-enhancing lesions at the site of treated glioma. Regions of interest (ROIs) were manually drawn at the contrast-enhancing lesion and peri-lesion edema areas. For calculation of standardised relative cerebral blood volume (rCBV) ratios, the same size ROIs were drawn at the area of contralateral hemisphere normal white matter on rCBV maps. At least five ROIs were selected at each lesion. The rCBV values were measured and the rCBV ratios were calculated. The maximum rCBV (rCBV(max) ) ratio at each region was chosen for analysis. The patients were divided into two groups: tumour recurrence and radiation injury. The mean rCBV(max) ratios were compared between the two groups. Results: The mean rCBV(max) ratio in the contrast-enhancing lesion was significantly higher in the tumour recurrence (4.36 ± 1.98) compared with that (1.28 ± 0.64) in the radiation injury (P < 0.01). The mean rCBV(max) ratio in the peri-lesion edema was also significantly higher in the tumour recurrence (1.79 ± 0.51) compared with that (0.85 ± 0.28) in the radiation injury (P < 0.05). A recurrent tumour was suggested when the rCBV(max) ratio >2.15 based on the receiver operating characteristic curve. Four patients with recurrent tumour and three with radiation injury were misclassified. Conclusion: PWI is a useful method to distinguish tumour recurrence and radiation injury. |
| | |
Authors:
|
Jun-Ling Xu; Da-Peng Shi; She-Wei Dou; Yong-Li Li; Feng-Shan Yan |
Related Documents
:
|
15249976 - Magnetic resonance imaging of obstetrical brachial plexus injuries. 21184956 - Magnamosis ii: magnetic compression anastomosis for minimally invasive gastrojejunostom... 21733206 - Cardiac computed tomography and conventional angiography in the diagnosis of congenital... 2952146 - Computed tomography of humeral head cup arthroplasties. a preliminary report. 15503106 - Combined mr spectroscopic imaging and diffusion tensor mri visualizes corticospinal tra... 20404436 - Opechowski-guccione-like symbols labelling magnetic space groups independent of tabulat... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of medical imaging and radiation oncology Volume: 55 ISSN: 1754-9485 ISO Abbreviation: J Med Imaging Radiat Oncol Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2011-12-06 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101469340 Medline TA: J Med Imaging Radiat Oncol Country: Australia |
Other Details:
|
Languages: eng Pagination: 587-94 Citation Subset: IM |
Copyright Information:
|
© 2011 The Authors. Journal of Medical Imaging and Radiation Oncology © 2011 The Royal Australian and New Zealand College of Radiologists. |
Affiliation:
|
Department of Radiology, Henan Provincial People's Hospital, Zhengzhou, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Nipple discharge in a screening programme: Imaging findings with pathological correlation.
Next Document: Dosimetric evaluation of conventional radiotherapy, 3-D conformal radiotherapy and direct machine pa...