| Distinction between Clostridium botulinum type A strains associated with food-borne botulism and those with infant botulism in Japan in intraintestinal toxin production in infant mice and some other properties. | |
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MedLine Citation:
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PMID: 1905658 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two strains of Clostridium botulinum type A associated with food-borne botulism and six strains associated with infant botulism in Japan were compared in intraintestinal toxin production in infant mice, in vitro toxin and hemagglutinin production, molecular sizes of the toxins, and some other properties. The infant botulism-associated strains, producing M toxin (Mr 300 kDa) but no hemagglutinin, showed significantly lower 50% infective doses in infant mouse intestines. The antigenicities of the toxin differed between the two groups, while the biochemical properties of the cultures did not. Besides infant botulism-associated strains, this set of properties were found only in a strain isolated from honey of South American origin. |
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Authors:
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K Tabita; S Sakaguchi; S Kozaki; G Sakaguchi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: FEMS microbiology letters Volume: 63 ISSN: 0378-1097 ISO Abbreviation: FEMS Microbiol. Lett. Publication Date: 1991 Apr |
Date Detail:
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Created Date: 1991-08-05 Completed Date: 1991-08-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7705721 Medline TA: FEMS Microbiol Lett Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 251-6 Citation Subset: IM |
Affiliation:
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Osaka Prefectural Institute of Public Health, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Botulinum Toxins / biosynthesis*, chemistry, immunology Botulism / microbiology* Clostridium botulinum / isolation & purification, metabolism, pathogenicity* Feces / microbiology Food Microbiology Hemagglutinins / biosynthesis Honey Humans Immunodiffusion Infant Intestines / microbiology* Japan Mice Molecular Weight Spores, Bacterial |
| Chemical | |
Reg. No./Substance:
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0/Botulinum Toxins; 0/Hemagglutinins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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