| Distinct basal ganglia hyperechogenicity in idiopathic basal ganglia calcification. | |
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MedLine Citation:
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PMID: 20803519 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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We report a 67-year-old patient with idiopathic basal ganglia calcification (IBGC). He presented with progressive cognitive impairment, frontal lobe dysfunction, mild leg spasticity, and levodopa (L-dopa)-responsive parkinsonism. Transcranial sonography (TCS) revealed marked hyperechogenicity of the basal ganglia and periventricular spaces bilaterally. The detected signal alterations showed a fairly symmetric distribution and corresponded to the hyperintense calcifications depicted on the computer tomography brain scan. The combination of symmetric hyperechogenic areas adjacent to the lateral ventricles and of the basal ganglia may serve as an imaging marker characteristic of IBGC. Hyperechogenicity due to extended basal ganglia calcification as presented here is distinct from the pattern of hyperechogenicity caused by heavy metal accumulation, which is described to be less striking. In addition to atypical parkinsonian syndromes such as progressive supranuclear palsy and multiple system atrophy, IBGC is thus another differential diagnosis of parkinsonism with basal ganglia hyperechogenicity. |
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Authors:
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Norbert Brüggemann; Susanne A Schneider; Thurid Sander; Christine Klein; Johann Hagenah |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Movement disorders : official journal of the Movement Disorder Society Volume: 25 ISSN: 1531-8257 ISO Abbreviation: Mov. Disord. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8610688 Medline TA: Mov Disord Country: United States |
Other Details:
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Languages: eng Pagination: 2661-4 Citation Subset: IM |
Copyright Information:
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© 2010 Movement Disorder Society. |
Affiliation:
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Schilling Section of Clinical and Molecular Neurogenetics, University of Lübeck, Lübeck, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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